Open Startup
Investment vehicle backing Africa’s boldest science ventures.
Openers First is a $3M Special Purpose Vehicle (SPV) deploying rapid $20K–$50K first checks via SAFE notes into science and deep tech ventures tackling Africa’s biggest health and climate challenges, targeting approximately 50 companies over five years.
Investment & impact strategy: Openers First is embedded within Open Startup, leveraging 10 years of science venture acceleration. Through a founder-to-founder flywheel, investment returns are recycled into the ecosystemcreating a self-sustaining model where successful ventures fuel the next generation of science entrepreneurs.

Fund Name: Openers First
Themes: Tech-enabled Solutions | Health | Climate Adaptation
Regions/Countries of activity or interest: Africa
Organisation HQ: United States of America
Expected Final Fund Size: USD 3,000,000
Stage of Fund Deployment: Currently Fundraising – Evergreen Fund / Open-ended Vehicle
Deployment Type: Venture Capital
Types of Investors: Foundations, Family Offices, Development Finance Institutions
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