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Open Startup

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Investment vehicle backing Africa’s boldest science ventures.

Openers First is a $3M Special Purpose Vehicle (SPV) deploying rapid $20K–$50K first checks via SAFE notes into science and deep tech ventures tackling Africa’s biggest health and climate challenges, targeting approximately 50 companies over five years.

Investment & impact strategy: Openers First is embedded within Open Startup, leveraging 10 years of science venture acceleration. Through a founder-to-founder flywheel, investment returns are recycled into the ecosystemcreating a self-sustaining model where successful ventures fuel the next generation of science entrepreneurs.

Fund Name: Openers First

Themes: Tech-enabled Solutions | Health | Climate Adaptation

Regions/Countries of activity or interest: Africa

Organisation HQ: United States of America

Expected Final Fund Size: USD 3,000,000

Stage of Fund Deployment: Currently Fundraising – Evergreen Fund / Open-ended Vehicle

Deployment Type: Venture Capital

Types of Investors: Foundations, Family Offices, Development Finance Institutions



The information presented on this page has been provided by the participating organisation. Building Bridges publishes this information for general informational purposes only in connection with Building Bridges 2026. Building Bridges has not independently verified the information and does not endorse, recommend or make any representation regarding any organisation, product, service, strategy, investment opportunity or claim described herein. The participating organisation is responsible for the accuracy, completeness and regulatory compliance of the information it provides.